Recombinant Human ADPRH/ARH1 Protein (His Tag)
SKU: PKSH032047-50
Recombinant Human ADPRH/ARH1 Protein (His Tag)
| SKU # | PKSH032047 |
| Expression Host | E.coli |
Description
| Synonyms | ADP-Ribose-L-Arginine Cleaving Enzyme, ADP-Ribosylarginine Hydrolase, ADPRH, ARH1, [Protein ADP-Ribosylarginine] Hydrolase |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Leu357 |
| Accession | P54922 |
| Calculated Molecular Weight | 41.7 kDa |
| Observed Molecular Weight | 39 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 50% Glycerol, pH 7.4. |
| Reconstitution | Not Applicable |
Background
ADP-Ribosylarginine Hydrolase (ADPRH) belongs to the ADP-Ribosylglycohydrolase family. ADPRH catalyzes removal of mono-ADP-ribose from arginine residues of proteins in the ADP-Ribosylation cycle, which is a post-translation modification that includes the addition of one or more ADP-ribose moieties. These reactions are related to cell signaling and the control of many cell processes, such as DNA repair and cell apoptosis. In addition, ADPRH binds with magnesium ion and possess ADP-ribosylarginine hydrolase activity.