Recombinant Cynomolgus VSIR Protein (His Tag)
SKU: PKSQ050016-50
Recombinant Cynomolgus VSIR Protein (His Tag)
| SKU # | PKSQ050016 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | C10orf54, Platelet receptor Gi24, SISP1, Sisp-1, Stress-induced secreted protein-1 |
| Species | Cynomolgus macaques |
| Expression Host | HEK293 Cells |
| Sequence | Phe33-Ala194 |
| Accession | A0A2K5UV12 |
| Calculated Molecular Weight | 19.2 kDa |
| Observed Molecular Weight | 30-50 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
platelet receptor Gi24 is a single-pass type I membrane protein, and located at the cell surface. The protein can be cleaved by MMP14, and stimulate MMP14-mediated MMP2 activation. It is participated in the BMP signaling pathway. It also regulates the CD4-pasitive, alpha-beta T cell proliferation, and T cell cytokine production negatively. However, the protein can regulate stem cell differentiation positively.