RBFOX2 Polyclonal Antibody Reactivity Human
SKU: E-AB-52909-200
RBFOX2 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52909 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human RBFOX2 |
| Abbre | RBFOX2 |
| Synonyms | FOX2, FXH, Fox 1 homologue, Fox-1 homolog B, HNRBP2, HRNBP2, Hexaribonucleotide-binding protein 2, RBFOX2, RFOX2, RNA binding motif protein 9, RNA binding protein 9, RNA binding protein fox-1 homolog 2, RNA-binding moti, Repressor of tamoxifen transcriptional activity |
| Swissprot | |
| Cellular Localization | Nucleus. Cytoplasm. |
| Concentration | 0.84 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:300 |
Background
This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene.