RAPGEF1 Polyclonal Antibody
SKU: E-AB-19964-200
RAPGEF1 Polyclonal Antibody
| SKU # | E-AB-19964 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human RAPGEF1 |
| Abbre | RAPGEF1 |
| Synonyms | C3G, C3G protein, CRK SH3 binding GNRP, CRK SH3-binding GNRP, DKFZp781P1719, GRF 2, GRF2, Guanine nucleotide releasing factor 2, Guanine nucleotide releasing factor 2 (specific for crk proto oncogene), Guanine nucleotide-releasing factor 2, OTTHUMP00000064558, Prote |
| Swissprot | |
| Concentration | 1.32 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:40-1:200 |
Background
This gene encodes a human guanine nucleotide exchange factor.It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases.This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation.Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.