PRKAR1B Polyclonal Antibody Store at -20°C
SKU: E-AB-16033-200
PRKAR1B Polyclonal Antibody Store at -20°C
| SKU # | E-AB-16033 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human PRKAR1B |
| Abbre | PRKAR1B |
| Synonyms | KAP1, PKARI beta, PRKAR 1, PRKAR 1B, PRKAR1, PRKAR1B protein, Prkar1b, Protein kinase cAMP dependent regulatory type I beta, RIbeta, cAMP dependent protein kinase type I beta regulatory subunit, cAMP-dependent protein kinase type I-beta regulatory subunit |
| Swissprot | |
| Cellular Localization | Cytosol, Plasma Membrane, Other locations: cAMP-dependent protein kinase complex, ciliary base. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion transport, and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP.