PRDX3 Polyclonal Antibody Store at -20°C
SKU: E-AB-14313-200
PRDX3 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14313 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human PRDX3 |
| Abbre | PRDX3 |
| Synonyms | AOP 1, AOP-1, AOP1, Antioxidant protein 1, HBC189, MER5, MGC104387, MGC24293, PRDX3, PRO1748, PRX III, PRX3, Peroxiredoxin III, Peroxiredoxin-3, Protein MER5 homolog, Prx-III, SP 22, SP-22, SP22, Thioredoxin dependent peroxide reductase m, mitochondrial, peroxiredoxin 3 |
| Swissprot | |
| Calculated MW | 28 kDa |
| Cellular Localization | Mitochondrion. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
Background
This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene.