Polysciences Inc. Poly(Dioxanone-Co-Lactide-Co-Glycolide), 90:5:5, IV 2.2 dL/g
SKU: 50079-25
Polysciences Inc. Poly(Dioxanone-Co-Lactide-Co-Glycolide), 90:5:5, IV 2.2 dL/g
MSE Supplies offers polymer reagents from Polysciences Inc.
CAS Number: N/A
Linear Formula: (C4H6O3)m(C3H4O2)n
Product Overview
Poly(Dioxanone-co-lactide-co-glycolide) (PDO-PLGA) is a biodegradable and biocompatible copolymer used in biomedical devices including staples, sutures, meshes, coatings, and controlled drug delivery. PDO-PLGA is degraded by hydrolysis via ester linkages and has a biodegradation timeframe in months. The addition of lactide and glycolide also denote greater flexibility to the polymer structure.
Shipping Requirements: Dry Ice
Synonyms/Acronyms: PDO-PLGA; PDO-PLA-PLGA
Properties
Viscosity: ~2.2 dL/g [i.v.]
Appearance: White to off-white solid
Molecular Weight: -
Biodegradation Time: ~ Months
References
1. Jiang, Zhaozhong, et al. "Lipase-catalyzed copolymerization of ω-pentadecalactone with p-dioxanone and characterization of copolymer thermal and crystalline properties." Biomacromolecules 8.7 (2007): 2262-2269.
https://doi.org/10.1021/bm070138a
Safety and Storage
Hazards: Harmless - use normal precautions; Hygroscopic
Handling: Gloves & fume hood
Storage: Protect from moisture. Store at -20°C.
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