PNPO Polyclonal Antibody
SKU: E-AB-19759-200
PNPO Polyclonal Antibody
| SKU # | E-AB-19759 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human PNPO |
| Abbre | PNPO |
| Synonyms | EC 1.4.3.5, FLJ10535, PDXPO, PNPO, Pyridoxal 5' phosphate synthase, Pyridoxamine phosphate oxidase , Pyridoxamine-phosphate oxidase, Pyridoxine-5'-phosphate oxidase, pyridoxamine 5' phosphate oxidase, pyridoxine 5' phosphate oxidase |
| Swissprot | |
| Calculated MW | 30 kDa |
| Observed MW | Refer to figures |
| Concentration | 0.9 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Metabolism, Neuroscience, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:20-1:100 |
Background
The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy.