Phospho-FOXO3 (Ser253) Polyclonal Antibody
SKU: E-AB-20878-200
Phospho-FOXO3 (Ser253) Polyclonal Antibody
| SKU # | E-AB-20878 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC-p, IF |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC-p, IF |
| Clonality | Polyclonal |
| Immunogen | Synthesized peptide derived from human FoxO3A around the phosphorylation site of Ser253 |
| Synonyms | AF6q21, AF6q21 protein, DKFZp781A0677, FKHR2, FKHRL 1, FKHRL1, FKHRL1P2, Forkhead (Drosophila) homolog (rhabdomyosarcoma) like 1, Forkhead Drosophila homolog of in rhabdomyosarcoma , Forkhead box O3, Forkhead box O3A, Forkhead box protein O3, Forkhead box protein O3A |
| Swissprot | |
| Calculated MW | 71 kDa |
| Observed MW | 97 kDa |
| Cellular Localization | Cytoplasm>cytosol. Nucleus. Translocates to the nucleus upon oxidative stress and in the absence of survival factors. |
| Tissue Specificity | Ubiquitous |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:100-1:300 |
| IF | 1:200-1:1000 |
Background
Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'.