NTAN1 Polyclonal Antibody Reactivity Human
SKU: E-AB-52879-200
NTAN1 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52879 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human NTAN1 |
| Abbre | NTAN1 |
| Synonyms | N terminal Asn amidase, N terminal asparagine amidase , N terminal asparagine amidohydrolase, NTN-amidase, PNAA , PNAD , Protein N-terminal Asn amidase, Protein N-terminal asparagine amidase, Protein N-terminal asparagine amidohydrolase, Protein NH2-terminal aspar |
| Swissprot | |
| Cellular Localization | Cytoplasmic |
| Concentration | 1.32 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:300 |
Background
The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms.