NLRC4 Polyclonal Antibody Reactivity Human
SKU: E-AB-52183-200
NLRC4 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52183 |
| Reactivity |
Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human NLRC4 |
| Abbre | NLRC4 |
| Synonyms | CARD, CARD 12, CARD LRR and NACHT containing protein, CARD LRR and NACHT containing protein 1, CARD12, Caspase recruitment domain containing protein 12, Caspase recruitment domain family member 12, Caspase recruitment domain-containi, and NACHT-containing protein |
| Swissprot | |
| Cellular Localization | Cytoplasm. Cytoplasmic filaments. |
| Concentration | 0.9 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism, Immunology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants.