NFATC3 Polyclonal Antibody Store at -20°C
SKU: E-AB-14243-200
NFATC3 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14243 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human NFATC3 |
| Abbre | NFATC3 |
| Synonyms | C80703, D8Ertd281e, NF AT4, NF ATc3, NF-AT4, NF-ATc3, NFAC3, NFATc3, NFATx, Nuclear factor of activated T cells, Nuclear factor of activated T-cells, T cell transcrip, calcineurin dependent 3, cytoplasmic, cytoplasmic 3, nuclear factor of activated T cells |
| Swissprot | |
| Cellular Localization | Cytoplasm. Nucleus. Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in the regulation of gene transcription. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:100-1:300 |
Background
The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex.This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component.Other members of this family participate to form this complex also.The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes.Several transcript variants encoding distinct isoforms have been identified for this gene.