NAPRT Polyclonal Antibody Reactivity Human
SKU: E-AB-52878-200
NAPRT Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52878 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human NAPRT |
| Abbre | NAPRT |
| Synonyms | FHA HIT interacting protein, FHA-HIT-interacting protein, FHIP, NAPRT1, NAPRTase, Nicotinate phosphoribosyltransferase, Nicotinate phosphoribosyltransferase domain containing 1, Nicotinate phosphoribosyltransferase domain-containing protein 1, Nicotinic acid phos |
| Swissprot | |
| Cellular Localization | Cytoplasm>cytosol. |
| Concentration | 0.66 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cell Biology, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:300 |
Background
Nicotinic acid (NA) is a coenzyme in cellular redox reactions,and is an essential component of metabolic pathways in all living cells. NAPRT1 (Nicotinate phosphoribosyltransferase) is essential for increasing cellular NAD levels and,thus,to prevent oxidative stress of cells. NAPRT1 converts Nicotinic acid (NA; niacin) to NA mononucleotide (NaMN),which is then converted to NA adenine dinucleotide (NaAD),and finally to nicotinamide adenine dinucleotide (NAD).