MT3 Polyclonal Antibody Store at -20°C
SKU: E-AB-15198-200
MT3 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-15198 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human MT3 |
| Abbre | MT3 |
| Synonyms | GIF, GIFB, GRIF, Growth inhibitory factor, MT III, MT-3, MT-III, MT3, Metallothionein 3, Metallothionein 3 (growth inhibitory factor (neurotrophic)), Metallothionein III, Metallothionein-3, Metallothionein-III, Mt 3, ZnMT3 |
| Swissprot | |
| Cellular Localization | Cytoskeleton, microtubule, Cytosol, Endoplasmic reticulum, rough endoplasmic reticulum, Extracellular region or secreted, extracellular space, Mitochondrion, mitochondrial outer membrane, Plasma Membrane, Other locations: astrocyte end-foot, axon, cytoplasm, dendritic spine, inclusion body, intracellular, perinuclear region of cytoplasm, postsynaptic density, ribosome, synaptic vesicle. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Metabolism, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
Metallothionein (MT) is a sulfhydryl- and cysteine-rich protein found in micro-organisms, plants and all invertebrate and vertebrate animals. Metallothioneins are a group of ubiquitous low-molecular-weight proteins that have functional roles in cell growth, repair and differentiation. Metallothionein are implicated primarily in metal ion detoxification as they are essential for the protection of cells against the toxicity of cadmium, mercury and copper. Metallothioneins are known to be broadly expressed in heart, liver, kidney, breast and testis tissue. Metallothionein 3, also known as MT-3 or GIFB (growth inhibitory factor), is a 68 amino acid protein that belongs to the type 1 family and Metallothionein superfamily. While highly expressed in astrocytes of the normal human brain, Metallothionein 3 expression is reduced in the brains of patients with Alzheimer disease.