MGLL Polyclonal Antibody Store at -20°C
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MGLL Polyclonal Antibody Store at -20°C
| SKU # | E-AB-13423 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human MGLL |
| Abbre | MGLL |
| Synonyms | EC 3.1.1.23, HU K5, HU-K5, HUK5, Lysophospholipase homolog, Lysophospholipase like, Lysophospholipase-like, MAGL, MGL, MGLL, Monoacylglycerol lipase, Monoglyceride lipase |
| Swissprot | |
| Cellular Localization | Cytosol, Endoplasmic reticulum, endoplasmic reticulum membrane, Nucleus, nucleoplasm, Plasma Membrane, Other locations: extrinsic component of membrane, membrane. |
| Concentration | 0.9 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.