MBTPS2 Polyclonal Antibody
SKU: E-AB-52057-200
MBTPS2 Polyclonal Antibody
| SKU # | E-AB-52057 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human MBTPS2 |
| Abbre | MBTPS2 |
| Synonyms | site 2, BRESEK, Endopeptidase S2P, IFAP, KFSDX, MBTP2, MBTPS2, Membrane bound transcription factor site 2 protease, Membrane-bound transcription factor site-2 prot, membrane-bound transcription factor peptidase, membrane-bound transcription factor protease |
| Swissprot | |
| Calculated MW | 57 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Membrane. Cytoplasm. |
| Concentration | 0.9 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cell Biology, Cardiovascular, Metabolism, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:10-1:50 |
Background
This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.