KCNN1 Polyclonal Antibody Reactivity Human
SKU: E-AB-52082-200
KCNN1 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52082 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human KCNN1 |
| Abbre | KCNN1 |
| Synonyms | KCNN 1, KCNN1, KCa2.1, Kcnn1, Potassium intermediate/small conductance calcium activated channel subfamily N member 1, SK, SK1, SKCa 1, SKCa1, Small conductance calcium activated potassium channel protein 1, Small conductance calcium-activated potassium chann, hSK1 |
| Swissprot | |
| Cellular Localization | Membrane. |
| Concentration | 1.56 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:300 |
Background
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes.