ISCU Polyclonal Antibody Reactivity Human
SKU: E-AB-52700-200
ISCU Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52700 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human ISCU |
| Abbre | ISCU |
| Synonyms | 2310020H20Rik, HML, ISCU, Iron sulfur cluster assembly enzyme ISCU mitochondrial, Iron sulfur cluster scaffold homolog, Iron sulfur cluster scaffold homolog (E. coli), Iron-sulfur cluster assembly enzyme ISCU, IscU iron sulfur cluster scaffold homolog, Iscu, hnifU |
| Swissprot | |
| Cellular Localization | Cytoplasm. Nucleus and Mitochondrion. |
| Concentration | 0.78 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Metabolism, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:40-1:200 |
Background
This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold.Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response.Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion.Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis.A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein.A pseudogene of this gene is present on chromosome 1.