IRX5 Polyclonal Antibody
SKU: E-AB-52043-200
IRX5 Polyclonal Antibody
| SKU # | E-AB-52043 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human IRX5 |
| Abbre | IRX5 |
| Synonyms | HMMS, Homeodomain Protein IRX-2A, Homeodomain Protein IRXB2, IRX2A, IRXB2, Iroquois Homeobox 5 |
| Swissprot | |
| Calculated MW | 50 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Nucleus |
| Concentration | 1.08 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Neuroscience, Epigenetics and Nuclear Signaling, Cardiovascular |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
This gene encodes a member of the iroquois homeobox gene family, which are involved in several embryonic developmental processes. Knockout mice lacking this gene show that it is required for retinal cone bipolar cell differentiation, and that it negatively regulates potassium channel gene expression in the heart to ensure coordinated cardiac repolarization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.