INI-1 Monoclonal Antibody Stored at -20°C
SKU: ELAB6932-M-0.1
INI-1 Monoclonal Antibody Stored at -20°C
Product Details
| Host | Mouse |
| Reactivity | Human |
| Applications | IHC-P |
| Synonyms | INI-1 |
| Cellular Localization | nucleus |
| Tissue Specificity | Breast cancer |
| Storage | The concentrated should be stored at -20°C protecting from light,Valid for 12 months. |
| Shipping | Ice bag |
Background
INI-1, located on chromosome 22q11.2, is a member of the SWI/SWF chromatin remodeling complex and is expressed in all normal tissues. INI-1 encodes a protein of HSWI/SNF chromatin remodeling complex with unknown function, which is prone to mutation and deletion in malignant rhabdoid tumors (MRT). "In most malignant rhabdoid tumors (including atypical teratoma/rhabdoid tumor of the central nervous system in children) and epithelioid sarcomas, INI-1 is inactivated, and the majority of medulloblastomas and primitive neuroectodermal tumors express INI-1."