IKZF3 Polyclonal Antibody Store at -20°C
SKU: E-AB-10975-200
IKZF3 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-10975 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human IKZF3 |
| Abbre | IKZF3 |
| Synonyms | AIO, Aiolos, IKAROS family zinc finger 3, IKAROS family zinc finger 3 (Aiolos), IKZF 3, IKZF3, Ikaros family zinc finger protein 3, Zinc finger pr, Zinc finger protein Aiolos, Zinc finger protein subfamily 1A 3 (Aiolos), zinc finger DNA binding protein Aiolos |
| Swissprot | |
| Cellular Localization | Nucleus. Cytoplasm. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.