IFT57 Polyclonal Antibody Reactivity Human
SKU: E-AB-52949-200
IFT57 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52949 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human IFT57 |
| Abbre | IFT57 |
| Synonyms | CDNA FLJ10147 fis clone HEMBA1003369, DERP 8, DERP8, Dermal papilla derived protein 8, Dermal papilla-derived protein 8, ESRRBL1 protein, Esrrbl 1, Esrrbl1, Estrogen related receptor beta like 1, Estrogen related receptor beta like protein 1, Estrogen-related recep |
| Swissprot | |
| Cellular Localization | Cytoplasm>cytoskeleton>cilium basal body. Concentrates within the inner segment of cilia. |
| Concentration | 1.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:300 |
Background
Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.