HSD3B1 Polyclonal Antibody Store at -20°C
SKU: E-AB-11310-200
HSD3B1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-11310 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human HSD3B1 |
| Abbre | HSD3B1 |
| Synonyms | 3BETAHSD, HSD3B, HSDB3, HSDB3A, I, SDR11E1 |
| Swissprot | |
| Cellular Localization | Endoplasmic reticulum, endoplasmic reticulum membrane, smooth endoplasmic reticulum membrane, Mitochondrion, mitochondrial inner membrane, mitochondrial intermembrane space, Other locations: integral component of membrane. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
HSD3B1 is a human gene that encodes for a 3beta-hydroxysteroid dehydrogenase/delta(5)-delta(4)isomerase type I or hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1.While it can carry out the same function as HSD3B2, it localizes primarily to different tissues, such as the placenta and nonsteroidogenic tissues. Its requirement for the production of progesterone by the placenta, which has a vital role in pregnancy, may be one reason why no disease based on mutations in this gene has been identified to date.