HSD17B12 Polyclonal Antibody Store at -20°C
SKU: E-AB-11302-200
HSD17B12 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-11302 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human HSD17B12 |
| Abbre | HSD17B12 |
| Synonyms | 12, 17 beta HSD 12, 17 beta hydroxysteroid dehydrogenase 12, 17-@beta-HSD XII, 17-@beta-hydroxysteroid dehydrogenase XII, 17-beta-HSD 12, 17-beta-hydroxysteroid dehydrogenase 12, 17beta HSD type 12, 3 ketoacyl CoA reductase, 3-, 3-ketoacyl-CoA reductase, short chain |
| Swissprot | |
| Calculated MW | 34 kDa |
| Cellular Localization | Endoplasmic reticulum membrane. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cell Biology, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:200-1:1000 |
| IHC | 1:50-1:200 |
Background
This gene encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation. Catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion of E1 to E2 in women.