HMGCS2 Polyclonal Antibody Store at -20°C
SKU: E-AB-16483-200
HMGCS2 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-16483 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human HMGCS2 |
| Abbre | HMGCS2 |
| Synonyms | 3 hydroxy 3 methylglutaryl Coenzyme A synthase 2, 3 hydroxy 3 methylglutaryl Coenzyme A synthase 2 (mitochondrial), 3 hydroxy 3 methylglutaryl coenzyme A synthase, 3-hydroxy-3-methylglutaryl coenzyme A synthase, HMCS2, HMG CoA synthase, HMG-CoA synthase, HMGCS 2 |
| Swissprot | |
| Calculated MW | 57 kDa |
| Cellular Localization | Mitochondrion. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Metabolism, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:100-1:300 |
Background
The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.