HMBS Polyclonal Antibody Reactivity Human
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HMBS Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52611 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human HMBS |
| Abbre | HMBS |
| Synonyms | Chester type, HEM3, HMBS, Hydroxymethylbilane synthase, PBG D, PBG-D, PBGD, PORC, Porphobilinogen deaminase, Pre uroporphyrinogen synthase, Pre-uroporphyrinogen synthase, UPS, Uroporphyrinogen I synthase, Uroporphyrinogen I synthetase, acute, porphyria |
| Swissprot | |
| Cellular Localization | Cytoplasm. |
| Concentration | 0.78 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Cell Biology, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:30-1:150 |
Background
This gene encodes a member of the hydroxymethylbilane synthase superfamily.The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane.Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria.Alternatively spliced transcript variants encoding different isoforms have been described.