HMB-45 Monoclonal Antibody stored at 2~8°C
SKU: PA6942-1.5
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HMB-45 Monoclonal Antibody stored at 2~8°C
Product Details
| Host | Mouse |
| Reactivity | Human |
| Applications | IHC-P |
| Synonyms | HMB-45 |
| Cellular Localization | Cytoplasm |
| Tissue Specificity | melanoma |
| Storage | The RTU should be stored at 2~8°C protecting from light (Do not freeze),Valid for 12 months. |
| Shipping | Ice bag |
Background
HMB45 is a melanoma-associated antigen that is mainly expressed in immature melanocytes. It was also expressed in activated and neoplastic melanocytes and other neural crest-derived tumors. It was also expressed in normal breast epithelium, some normal sweat glands, sweat gland-derived tumors and angiomyolipoma, and occasionally in carcinoma. "It is more specific than S-100 or NKl/C3 for the diagnosis of malignant melanoma, but the sensitivity is less than 90%, especially in metastatic melanoma."