GFI1 Polyclonal Antibody
SKU: E-AB-19906-200
GFI1 Polyclonal Antibody
| SKU # | E-AB-19906 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human GFI1 |
| Abbre | GFI1 |
| Synonyms | GFI 1, GFI1, Growth factor independence 1, Growth factor independent 1, Growth factor independent protein 1, SCN2, ZNF 163, ZNF163, Zinc finger protein 163, Zinc finger protein Gfi 1, Zinc finger protein Gfi-1, Zinc finger protein Gfi1 |
| Swissprot | |
| Cellular Localization | Nucleus. |
| Concentration | 1.86 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:300 |
Background
This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor.This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis.It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters.Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections.Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.