FKTN Polyclonal Antibody
SKU: E-AB-19886-200
FKTN Polyclonal Antibody
| SKU # | E-AB-19886 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human FKTN |
| Abbre | FKTN |
| Synonyms | CMD1X, FCMD, FCMD gene, FKTN, Fukutin, Fukuyama type congenital muscular dystrophy protein, Fukuyama-type congenital muscular dystrophy protein, LGMD2M, MDDGA4, MDDGB4, MDDGC4, MGC126857, MGC134944, MGC134945, MGC138243, OTTHUMP00000021841, patient fukutin |
| Swissprot | |
| Calculated MW | 54 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Golgi apparatus membrane. |
| Concentration | 1.08 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Developmental biology, Tags and Cell markers |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
The protein encoded by this gene is a putative transmembrane protein that is localized to the cis-Golgi compartment, where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle. The encoded protein is thought to be a glycosyltransferase and could play a role in brain development. Defects in this gene are a cause of Fukuyama-type congenital muscular dystrophy (FCMD), Walker-Warburg syndrome (WWS), limb-girdle muscular dystrophy type 2M (LGMD2M), and dilated cardiomyopathy type 1X (CMD1X). Alternatively spliced transcript variants have been found for this gene.