EPM2A Polyclonal Antibody Reactivity Human
SKU: E-AB-52671-200
EPM2A Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52671 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human EPM2A |
| Abbre | EPM2A |
| Synonyms | EPM2, EPM2A, Epilepsy progressive myoclonus type 2 Lafora disease (laforin), Epilepsy progressive myoclonus type 2A Lafora disease (laforin), Epm2a, Epm2a gene, LAFPTPase, LD, LDE, Lafora PTPase, Laforin, MELF, RP3-466P17.2 |
| Swissprot | |
| Cellular Localization | Cytoplasm, Cytoplasm, Nucleus, Endoplasmic reticulum, Cell membrane, Nucleus, Also found in the nucleus, Endoplasmic reticulum, Cell membrane, Primarily associated with polyribosomes at the endoplasmic reticulum, also found at the plasma membrane and Cytoplasm, Under glycogenolytic conditions localizes to the nucleus. |
| Concentration | 1.32 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Metabolism, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:300 |
Background
This gene encodes a dual-specificity phosphatase that associates with polyribosomes.The encoded protein may be involved in the regulation of glycogen metabolism.Mutations in this gene have been associated with myoclonic epilepsy of Lafora.Alternative splicing results in multiple transcript variants.