ELP2 Polyclonal Antibody Store at -20°C
SKU: E-AB-14722-200
ELP2 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14722 |
| Reactivity | Human, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human ELP2 |
| Abbre | ELP2 |
| Synonyms | AU023723, ELP2, Elongation protein 2 homolog (S. cerevisiae), Elongator acetyltransferase complex subunit 2, Elongator complex protein 2, Epl2, FLJ10879, SHINC 2, SHINC-2, SHINC2, elongator protein 2, signal transducer and activator of transcription 3 interacti |
| Swissprot | |
| Cellular Localization | Cytoplasm. Nucleus. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Epigenetics and Nuclear Signaling, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:100-1:300 |
Background
One member of the STAT family, Stat3, participates in a wide range of biological processes including nephrogenesis, gliogenesis, hepatogenesis, T cell proliferation, inflammation and oncogenesis.Many of these responses are triggered by the IL-6 family of cytokines, which transduce their vital signals through a common gp130 receptor chain .A novel Stat3-Interacting Protein, StIP1, contains 12 WD40 repeats, which mediate protein-protein interactions .StIP1 exhibits an affinity for members of the JNK family and may play a specific role in regulating Stat3 activation.Overexpression of StIP1 blocks Stat3 activation, nuclear translocation and Stat3-dependent induction of a reporter gene, suggesting that StIP1 regulates the ligand-dependent activation of Stat3, probably by serving as a scaffold protein that promotes the interaction between JNK and the Stat3 substrate.