ELP1 Polyclonal Antibody
SKU: E-AB-52014-200
ELP1 Polyclonal Antibody
| SKU # | E-AB-52014 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ELP1 |
| Abbre | ELP1 |
| Synonyms | DKFZp781H1425, DYS, Dysautonomia (Riley Day syndrome hereditary sensory autonomic neuropathy type III), ELP 1, ELP1, Elongator complex protein 1, FD, FLJ12497, IK, IKAP, IkappaB kinase complex associated protein, IkappaB kinase complex-associated protein, ikbkap |
| Swissprot | |
| Cellular Localization | Cytoplasm. Nucleus. |
| Concentration | 0.9 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Epigenetics and Nuclear Signaling, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:30-1:150 |
Background
The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms.