DGKI Polyclonal Antibody
SKU: E-AB-19733-200
DGKI Polyclonal Antibody
| SKU # | E-AB-19733 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human DGKI |
| Abbre | DGKI |
| Synonyms | DAG kinase iota, DGK-iota, DGKI, Diacylglycerol kinase iota, Diglyceride kinase iota |
| Swissprot | |
| Cellular Localization | Cytosol, Nucleus, nucleoplasm, nucleus, Plasma Membrane, synaptic membrane, Other locations: axon terminus, cytoplasm, dendritic spine, excitatory synapse, guanyl-nucleotide exchange factor complex, neuronal cell body, perinuclear region of cytoplasm, postsynaptic density, presynaptic active zone, protein complex, synapse, synaptic vesicle. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:30-1:150 |
Background
This gene is a member of the type IV diacylglycerol kinase subfamily.Diacylglycerol kinases regulate the intracellular concentration of diacylglycerol through its phosphorylation, producing phosphatidic acid.The specific role of the enzyme encoded by this gene is undetermined, however, it may play a crucial role in the production of phosphatidic acid in the retina or in recessive forms of retinal degeneration.