DCP1A Polyclonal Antibody Store at -20°C
SKU: E-AB-11140-200
DCP1A Polyclonal Antibody Store at -20°C
| SKU # | E-AB-11140 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human DCP1A |
| Abbre | DCP1A |
| Synonyms | DCP1 decapping enzyme homolog A, DCP1A, Dcp1a, Decapping enzyme hDcp1a, Decapping mRNA 1A, HSA275986, Nbla00360, Putative protein product of Nbla00360, Smad4 interacting transcriptional co activator, Smad4-interact, mRNA decapping enzyme 1A, mRNA-decapping enzyme 1A |
| Swissprot | |
| Cellular Localization | Cytoplasm>P-body. Nucleus. Co-localizes with NANOS3 in the processing bodies (By similarity). Predominantly cytoplasmic, in processing bodies (PB). Nuclear, after TGFB1 treatment. Translocation to the nucleus depends on interaction with SMAD4. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:100-1:300 |
Background
Decapping is a key step in general and regulated mRNA decay.The protein encoded by this gene is a decapping enzyme.This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons.This protein also participates in the TGF-beta signaling pathway.Alternative splicing of this gene results in multiple transcript variants.