CD74 Monoclonal Antibody Synonyms CD74
SKU: PA6298-1.5
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CD74 Monoclonal Antibody Synonyms CD74
Product Details
| Host | Mouse |
| Reactivity | Human |
| Applications | IHC-P |
| Synonyms | CD74 |
| Cellular Localization | cell membrane |
| Tissue Specificity | Tonsil |
| Storage | The RTU should be stored at 2~8°C protecting from light (Do not freeze),Valid for 12 months. |
| Shipping | Ice bag |
Background
CD74 is a membrane binding subunit of the class II related invariant chain of the major histocompatibility complex. CD74 is mainly used to label lymphocytes in germinal center and in the mantle cell area of lymph nodes. This does not label plasma cells or thymocytes, but usually labels dendritic cells. About 90% of low-grade B-cell lymphoma and 20% of low-grade T-cell lymphoma are expressing CD74, but in high-grade lymphoma, the ability to distinguish B cells from T cells is decreased.