CD45 Monoclonal Antibody
SKU: E-AB-22009-200
CD45 Monoclonal Antibody
| SKU # | E-AB-22009 |
| Reactivity | Human |
| Host | Mouse |
| Applications | WB, IHC-p |
Product Details
| Isotype | IgG |
| Host | Mouse |
| Reactivity | Human |
| Applications | WB, IHC-p |
| Clonality | Monoclonal |
| Immunogen | Synthetic Peptide |
| Abbre | CD45 |
| Synonyms | B220, CD 45, CD45, CD45 antigen, CD45R, GP180, L-CA, LCA, LY5, Leukocyte common antigen, Ly-5, Ly5, Lyt-4, OTTHUMP00000033813, OTTHUMP00000033816, OTTHUMP00000033817, OTTHUMP00000038574, Protein tyros, Protein tyrosine phosphatase receptor type c polypeptide, homolog of, loc |
| Swissprot | |
| Calculated MW | 147 kDa |
| Observed MW | 147 kDa |
| Cellular Localization | Membrane |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Protein A purification |
| Research Areas | Cancer, Cardiovascular, Immunology, Neuroscience, Signal Transduction, Stem Cells |
| Clone No. | 3H3 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-300 |
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family.PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation.This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP.This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling.It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling.