CD1A Monoclonal Antibody
SKU: E-AB-22096-200
CD1A Monoclonal Antibody
| SKU # | E-AB-22096 |
| Reactivity | Human, Mouse, Rat |
| Host | Mouse |
| Applications | IHC-p, IF |
Product Details
| Isotype | IgG |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC-p, IF |
| Clonality | Monoclonal |
| Immunogen | Synthetic Peptide |
| Abbre | CD1 |
| Synonyms | CD 1a, CD1, CD1A, CD1A Antigen, CD1A antigen, CD1a, CD1a molecule, FCB 6, FCB6, HTA 1, HTA1, a polypeptide, cluster of differentiation 1 A, cortical thymocyte antigen CD1A, differentiation antigen CD1 alpha 3, epidermal dendritic cell marker CD1a, hTa1 thymocyte antigen |
| Swissprot | |
| Cellular Localization | Cell membrane. Endosome membrane. Subject to intracellular trafficking between the cell membrane and endosomes. Localizes to cell surface lipid rafts. |
| Tissue Specificity | Expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Protein A purification |
| Research Areas | Cancer, Immunology |
| Clone No. | 2A5 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:100-1:300 |
| IF | 1:50-200 |
Background
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin.The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells.The human genome contains five CD1 family genes organized in a cluster on chromosome 1.The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands.The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system.Alternatively spliced transcript variants have been observed, but their biological validity has not been determined.