ASL Polyclonal Antibody Store at -20°C
SKU: E-AB-14601-200
ASL Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14601 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human ASL |
| Abbre | ASL |
| Synonyms | ARLY, ASAL, ASL, Argininosuccinase, Argininosuccinate lyase, Arginosuccinase, EC 4.3.2.1 |
| Swissprot | |
| Cellular Localization | Cytosol, Extracellular region or secreted, extracellular exosome, Other locations: cytoplasm. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
This gene encodes a member of the lyase 1 family.The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle.Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency.A nontranscribed pseudogene is also located on the long arm of chromosome 22.Alternatively spliced transcript variants encoding different isoforms have been described.