AK6 Polyclonal Antibody Reactivity Human
SKU: E-AB-53058-200
AK6 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-53058 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human AK6 |
| Abbre | AK6 |
| Synonyms | AD-004, AK/ATPase, AK6, Adenylate kinase isoenzyme 6, Adrenal gland protein AD-004, CGI-137, CIP, Coilin-interacting nuclear ATPase protein, Dual activity adenylate kinase/ATPase, KAD6, TAF9, hCINAP |
| Swissprot | |
| Cellular Localization | Nucleus>nucleoplasm. Nucleus>Cajal body. Displays widespread diffuse nucleoplasmic distribution but not detected in nucleoli. Detected in Cajal bodies but not in all cells. |
| Concentration | 1.56 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
This gene encodes a protein that belongs to the adenylate kinase family of enzymes. The protein has a nuclear localization and contains Walker A (P-loop) and Walker B motifs and a metal-coordinating residue. The protein may be involved in regulation of Cajal body formation. In human, AK6 and TAF9 (GeneID: 6880) are two distinct genes that share 5' exons. Alternative splicing results in multiple transcript variants.AK6 (Adenylate Kinase 6) is a Protein Coding gene. Among its related pathways are Ribosome biogenesis in eukaryotes and Purine metabolism (REACTOME). GO annotations related to this gene include ATPase activity and adenylate kinase activity.