AIMP1 Polyclonal Antibody Store at -20°C
SKU: E-AB-13210-200
AIMP1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-13210 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human AIMP1 |
| Abbre | AIMP1 |
| Synonyms | AIMP 1, AIMP1, AIMP1/p43, ARS interacting multifunctional protein 1, Aimp1, Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1, EMAP 2, EMAP-2, EMAP-II, EMAP2, EMAPII, Endothelial monocyte activating, Endothelial monocyte activating polypeptide 2 |
| Swissprot | |
| Calculated MW | 34 kDa |
| Cellular Localization | Nucleus. Cytoplasm>cytosol. Cytoplasmic vesicle>secretory vesicle. Secreted. Endoplasmic reticulum. Golgi apparatus. Enriched in secretory vesicles of pancreatic alpha cells and secreted from the pancreas in response to low glucose levels (By similarity). Also secreted in response to hypoxia and both apoptotic and necrotic cell death. |
| Concentration | 1.1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling, Immunology, Tags and Cell Markers |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
Background
The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20.