ADGRE3 Polyclonal Antibody
SKU: E-AB-19802-200
ADGRE3 Polyclonal Antibody
| SKU # | E-AB-19802 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ADGRE3 |
| Abbre | ADGRE3 |
| Synonyms | EGF like module containing mucin like receptor EMR3, EMR 3, Egf like module containing mucin like hormone receptor like 3, Egf like module containing mucin like receptor 3 |
| Swissprot | |
| Calculated MW | 73 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cell membrane, Multi-pass membrane protein, EMR3 subunit alpha: Secreted, extracellular space, Note: A soluble form is also detected. |
| Concentration | 1.44 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Immunology, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:40-1:200 |
Background
This gene encodes a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing results in multiple transcript variants encoding different isoforms.