ADGRB1 Polyclonal Antibody Store at -20°C
SKU: E-AB-13084-200
ADGRB1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-13084 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human BAI1 |
| Abbre | ADGRB1 |
| Synonyms | B830018M07Rik, BAI 1, BAI1, Brain specific angiogenesis inhibitor 1, Brain-specific angiogenesis inhibitor 1, GDAIF, KIAA4089, R75078, mKIAA4089 |
| Swissprot | |
| Cellular Localization | Cell membrane. Likely to be concentrated at cell-cell adhesion sites. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53.