First dissolved in DMSO (up to 30 mg/ml) or in Water (up to 30 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 week.
Tribioscience U-18666A, Cholesterol Transport Inhibitor (TBI1075)
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Tribioscience U-18666A, Cholesterol Transport Inhibitor (TBI1075)
Research Use Only. Not intended for human use.
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Product Details
Formal Name: 3ß-[2-(Diethylamino)ethoxy]androst-5-en-17-one hydrochloride
Molecular Formula: C25H41NO2 ∙ HCl
Formula Weight: 387.61 ∙ 36.46
CAS Number: 3039-71-2
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 30 mg/ml) or in Water (up to 30 mg/ml).
Storage: RT
Stability: ≥ 2 years.
Applications
Cholesterol transport inhibitor
Functions
U18666A is an oxidosqualene reductase inhibitor. Inhibits the egress of cholesterol from late endosomes and lysosomes. Also used to study Niemann-Pick disease and for assessing the importance of molecular trafficking through the lysosomal pathway in other conditions.
Application Procedures