Tribioscience Palmitoylethanolamide, GPR55 Agonist; Endogenous Cannabinoid (TBI1297)

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SKU: TBI1297-20MG
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Tribioscience Palmitoylethanolamide, GPR55 Agonist; Endogenous Cannabinoid (TBI1297)

Research Use Only. Not intended for human use.

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Product Details

Formal Name: N-(2-hydroxyethyl)palmitamide

Alternate Names: PEA

Molecular Formula: C18H37NO2

Formula Weight: 299.50

CAS Number: 544-31-0

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).

Storage: -20°C

Stability: ≥ 2 years.

Applications

GPR55 agonist; endogenous cannabinoid

Functions

Endogenous cannabinoid. Weak ligand for CB1 (Ki=23.8 µM) and CB2 (Ki=13.9 µM) receptor.  Selective agonist at GPR55. Inhibits expression of fatty acid amide hydrolase (FAAH). Displays immunosuppressant and anti-inflammatory activity and reduces granuloma-induced hyperalgesia.

Application Procedures

First dissolved in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in water may be stored at -20°C for up to 3 months.