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Tribioscience Dofetilide, Herg Channel Blocker (TBI1151)

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SKU: TBI1151-10MG
Regular price $ 116.95

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Tribioscience Dofetilide, Herg Channel Blocker (TBI1151)

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Product Details

Formal Name: N-[4-(2-{[2-(4-Methanesulfonamidophenoxy)ethyl](methyl)amino}ethyl)phenyl]methanesulfonamide

Alternate Names: Tikosyn

Molecular Formula: C19H27N3O5S2

Formula Weight: 441.56

CAS Number: 115256-11-6

Purity: >98%

Formulation: Powder

Solubility: Soluble in DMSO (up to 25 mg/ml)

Storage: RT

Stability: ≥ 1 year.

Applications

Herg channel blocker

Functions

Dofetilide is a clinically useful class III antiarrhythmic that inhibits the rapid component of the delayed rectifier outward potassium current (IKr) via selective blockage of  the Kv11.1 (hERG) channel.

Application Procedures

First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.