TRIM27 Polyclonal Antibody Reactivity Mouse
SKU: E-AB-52224-200
TRIM27 Polyclonal Antibody Reactivity Mouse
| SKU # | E-AB-52224 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human TRIM27 |
| Abbre | TRIM27 |
| Synonyms | AW538890, DAAP-182E11.3, MGC189472, OTTHUMP00000029314, RFP, RFP transforming protein, RING finger protein 76, RNF76, Ret finger protein, Rfp1, TRI27, TRIM 27, Trim27, Tripartite motif containing 27, Tripartite motif containing protein 27, Tripartite motif protein TRIM2 |
| Swissprot | |
| Calculated MW | 58 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Nucleus. Cytoplasm. Nucleus>PML body. Nuclear or cytoplasmic depending on the cell type (By similarity). Colocalized with PML and EIF3S6 in nuclear bodies. |
| Concentration | 0.8 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:30-1:150 |
Background
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein.