Product Details
Formal Name: 9H-Indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one
Molecular Formula: C11H4N4O2S
Formula Weight: 224.18
CAS Number: 67200-34-4
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 20 mg/ml).
Storage: RT
Stability: ≥ 2 years.
Applications
E3 Ubiquitin ligase inhibitor
Functions
Small Molecule Enhancer of Rapamycin 3 (SMER3) is a specific inhibitor if the ubiquitin E3 ligase SCFMET30 both in vitro and in vivo.
Application Procedures
First dissolved in DMSO (up to 20 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 2 months.