Product Details
Formal Name: 3’-Amino-3’-deoxy-N6,N6-dimethyladenosine
Alternate Names: PAN
Molecular Formula: C12H18N6O3
Formula Weight: 294.32
CAS Number: 58-60-6
Purity: >98%
Formulation: powder
Solubility: Soluble in Water (up to 50 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
Nephropathy inducer
Functions
The nucleoside moiety of puromycin which does not inhibit protein synthesis or induce apoptosis. It acts as a glomerular epithelial cell toxin and as such is a useful tool for producing animal models of nephropathy, or puromycin aminonucleoside nephrosis (1-2.5 mg/100g rat body weight). Active in vivo.
Application Procedures
First dissolved in Water (up to 50 mg/ml), then diluted to aqueous buffer. Solutions in distilled water may be stored at -20°C for up to 2 months.