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Tribioscience Phenoxybenzamine HCl, Calmodulin Antagonist, Alpha Adrenergic Antagonist (TBI1237)

Tribioscience Phenoxybenzamine HCl, Calmodulin Antagonist, Alpha Adrenergic Antagonist (TBI1237)

SKU: TBI1237-100MG

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Tribioscience Phenoxybenzamine HCl, Calmodulin Antagonist, Alpha Adrenergic Antagonist (TBI1237)

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Product Details

Formal Name: N-(2-Chloroethyl)-N-(1-methyl-2-phenoxyethyl)benzylamine hydrochloride

Molecular Formula: C18H22ClNO · HCl

Formula Weight: 340.29

CAS Number: 63-92-3

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 50 mg/ml), or in Water (up to 15 mg/ml).

Storage: RT

Stability: ≥ 2 years.

Applications

Calmodulin antagonist, alpha adrenergic antagonist

Functions

Binds to and inhibits calmodulin in a calcium-dependent and irreversible manner (IC50= ca.1 μM). A classical irreversible α adrenergic antagonist. A useful tool for irreversible inhibition of calmodulin. Cell permeable.

Application Procedures

First dissolved in DMSO (up to 50 mg/ml), or in Water (up to 15 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.