First dissolved in DMSO (up to 50 mg/ml) or in Ethanol (up to 50 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or Ethanol may be stored at -20°C for up to 1 week.
Tribioscience Orlistat, DAG Lipase-a Inhibitor (TBI2448)
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Tribioscience Orlistat, DAG Lipase-a Inhibitor (TBI2448)
Research Use Only. Not intended for human use.
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Product Details
Formal Name: N-formyl-L-leucine (1S)-10[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester
Alternate Names: Ro18-0647; Tetrahydrolipstatin (-)
Molecular Formula: C29H53NO5
Formula Weight: 495.75
CAS Number: 96829-58-2
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 50 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
DAG lipase-a inhibitor
Functions
A lipase inhibitor which blocks the biosynthesis of 2-AG by inhibition of DAG lipase-α. Inhibits pancreatic lipase and other lipases but not PLA2. Inhibits fatty acid synthase and displays antitumor activity. Prevents fat absorption in the gut and is a clinically useful antiobesity agent.
Application Procedures